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Why should my doctor and I consider ZYMFENTRA?

If you and your doctor decide that you’re a candidate for infliximab, ZYMFENTRA™ may be right for you. Ask your doctor whether ZYMFENTRA may be a suitable treatment option to explore.

ZYMFENTRA is an FDA-approved medicine proven to help patients achieve remission. And because it can be injected at home, it offers convenience to allow you more freedom with fewer restraints.

Benefits of long-term at-home injections

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Convenience
of at home administration

IV Bag

No infusions

Why Zymfentra 4

Less Administration time

Why Zymfentra 3

No need to schedule time off from work or school

63% of patients with Crohn’s disease achieved remission at 1 year with ZYMFENTRA (vs. 30% for placebo)

40% of patients with Crohn’s disease achieved remission at 1 year with ZYMFENTRA without needing steroids (vs. 21% for placebo)

Results with ZYMFENTRA

In a clinical study, ZYMFENTRA was shown to help patients with Crohn’s disease achieve long-term remission.

Patient Crohn's Disease Diagram

How does ZYMFENTRA work to control Crohn’s disease?

ZYMFENTRA is a type of medicine called a biologic. Biologics are made of living organisms and are designed to target specific proteins in the body that cause inflammation. One common protein involved in inflammation is called tumor necrosis factor (TNF). Patients with IBD can have too much TNF in their bodies, causing their immune system to attack normal, healthy parts of the body. By targeting and blocking TNF, ZYMFENTRA lowers inflammation to help you feel better. The connection between the TNF-blocking activities of ZYMFENTRA and how ZYMFENTRA works in the body to treat patients is not fully understood.

How does ZYMFENTRA work to control Crohn’s disease?

ZYMFENTRA is a type of medicine called a biologic. Biologics are made of living organisms and are designed to target specific proteins in the body that cause inflammation. One common protein involved in inflammation is called tumor necrosis factor (TNF). Patients with IBD can have too much TNF in their bodies, causing their immune system to attack normal, healthy parts of the body. By targeting and blocking TNF, ZYMFENTRA lowers inflammation to help you feel better. The connection between the TNF-blocking activities of ZYMFENTRA and how ZYMFENTRA works in the body to treat patients is not fully understood.

Crohn’s disease can affect any part of the digestive tract. ZYMFENTRA lowers inflammation in these areas to help you feel better.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ZYMFENTRA?

ZYMFENTRA may cause serious side effects, including risk of infection and cancer.

Do not take ZYMFENTRA if you:

Before you receive ZYMFENTRA, tell your doctor about all of your medical conditions, including if you:

What should I avoid while taking ZYMFENTRA?

What are the possible side effects of ZYMFENTRA?
ZYMFENTRA can cause serious side effects, including:

The most common side effects include COVID-19, joint pain, respiratory infections such as sinus infections and sore throat, diarrhea, injection site reactions, high blood pressure, headache, urinary tract infections, abdominal pain, dizziness, and abnormal liver enzymes.

INDICATIONS

ZYMFENTRA is a prescription medicine used as an injection under the skin (subcutaneous injection) by adults for the maintenance treatment of moderately to severely active ulcerative colitis or moderately to severely active Crohn’s disease following treatment with an infliximab product given by intravenous infusion (IV).

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see the Medication Guide and talk with your healthcare provider.

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